Montserrat Carrascal
Biochemistry PhD.
CSIC/UAB Proteomics Laboratory, IIBB-CSIC
Office / Phone #:
M5-111 / 93 581 4854

Medical Shcool, Biochemistry Department, UAB, 08193
Cerdanyola (Barcelona), Espanya

1 R.E. Calaf, M. Carrascal, E. Gelpi and J. Abian. Quantitative analysis of mevinolinic acid in human plasma by HPLC negative ion tandem mass spectrometry Rapid Communications in Mass Spectrometry 11, 75-80 (1997)   
2 R.Daniel, E. Caminade, A. Martel, F. LeGoffic, D. Canosa, M. Carrascal and J. Abian. Mass spectrometric determination of the cleavage sites in E.coli Dihydroorotase induced by a cysteine specific reagent. J.Biological Chemistry  272 (43), 26934-26939 (1997)                                                                          
3 M.Carrascal, K.Schneider, R.E.Calaf,  S. van Leeuwen, D.Canosa, E.Gelpi and J.Abian. Quantitative electrospray LC-MS and LC-MS/MS in biomedicine. J.Pharm.Biomed.Anal., 17, 1129-1138 (1998)   
4 M.Valls, R.Bofill, N.Romerio-Isart, R.Gonzalez-Duarte, J.Abian, M.Carrascal, P.Gonzalez, Duarte, M. Capdevila and S.Atrian. Drosophila MTN: a metazoan copper-thionein related to fungal forms. FEBS Letters 467, 189-194 (2000)   
5 J.M.Nieto, C.Madrid, A.Prenafeta, E.Miquelay, C.Balsalobre, M.Carrascal,and A.Juarez. Expression of the hemolysin operon in Escherichia coli is modulated by a nucleoid-protein complex that includes the proteins hha and h-ns. Mol.Gen.Genet. 263, 349-358 (2000)   
6 A.Juarez, J.M.Nieto, E.Miquelay, C.Balsalobre, M.Carrascal and A.Juarez. Interaction of the nucleoid-associated proteins hha and h-nh to modulate expression of the hemolysisn operon in escherichia coli. Adv.Esp.Med.Biol. 485, 127-131(2000)   
7 R.E.Calaf, J. Peña, S. Paituby, M. Carrascal, M.Posada de la Paz, E.Gelpi and J.Abian. Automated strong cation exchange extraction of acylated phenylamino propanediols from oil samples for routine quantitation by HPLC-APCI/MS/MS. J.Agr. Food Chemistry 49, 5085-5091 (2001)   
8 A.J.Oosterkamp, M.Carrascal, D.Closa, G.Escolar, E.Gelpi and J.Abian. On line preconcentration micro liquid chromatography tandem mass spectrometric method for bradykinin analysis in plasma. J.Microcolumn Separations 13, 265-274 (2001)   
9 A.Muntasell, M.Carrascal, L.Serradell, P.vanVeelen, F.Verreck, F.Koning, G.Raposo, J.Abian and D.Jaraquemada. HLA-DR4 molecules in neuroendocrine epithelial cells associate to a heterogeneous repertoire of cytoplasmic and surface self-peptides. J.Immunol. 169, 5052-5060 (2002)   
10 M. Carrascal, S., O. Bachs and J. Abián. Identification of p21cip1 binding proteins by gel electrophoresis and capillary liquid chromatography microelectrospray tandem mass spectrometry. Proteomics 2,  455-468 (2002)  
11 E.Fernandez, M.Carrascal, F. Rousaud, J. Abian, A.Zorzano, M.Palacin and J.Chillaron. The rBAT-b 0,+AT heterodimer is the main apical reabsorption system for cystine in kidney. Am.J.Physiol.Renal Physiol. 283, F540-548 (2002).   
12 E.A.Castillo, J.Ayte, C.Chiva, A.Moldon, M.Carrascal, J.Abian, N.Jones and E.Hidalgo. Diethylmaleate activates de transcription factor PAP1 by covalent modification of critical cysteine residues. Mol.Microbiol. 45, 243-254 (2002)   
13 A.Descroix, A.Varenne, N.Goasdoue, J.Abian, M.Carrascal, R.Daniel and P.Gareil. Mon-aqueous capillary electrophoresis of positional isomers of a sulphated monosaccharide. J.Chromatogr. A 987, 467-476 (2003)   
14 S.Guil, R.Gattoni, M.Carrascal, J.Abian, J.Stevenin and Montse Bach-Elias. Hnrnp A1 and Sr Proteins Regulate the Alternative Splicing of Proto-Oncogen C-H-Ras, Balancing the Relative Abundance of Two Alternative H-Ras Proteins, P19 and P21. Mol.Cell Biol. 23, 2927-2941 (2003)                    
15 I.Forne, M.Carrascal, L.Martinez-Lostao, J.Abian, J.L. Rodriguez-Sanchez and C.Juarez. Identification of the Autoantigen Hb As the Barrier-To-Autointegration Factor. J.Biological Chemistry  278(50), 50641-50644, (2003)    
16 S.Campo, M.Carrascal, M. Coca, J.Abian and B. San Segundo. The Defence Response of Germinating Maize Embryos Against Fungal Infection: A Proteomics Approach. Proteomics 4(2), 383-396 (2004)   
17 C.Quero, N.Colomé, M.R.Prieto, M.Carrascal, M.Posada, E.Gelpí and J. Abian. Determination of Protein Markers in Human Serum. Analysis of Protein Expression On Toxic Oil Syndrome Studies. Proteomics 2, 303-315 (2004)   
18 M.Carrascal, K.Schneider, C.Peralta, G.Escolar, E.Gelpí and J.Abián. Isoform specific quantification of endothelins in HUVEC culture supernatans by on line HPLC/electrospray mass spectrometry. Biomedical Chromatography  18, 388-395 (2004)   
19 M.R.Sarrias, O. Padilla, Y. Monreal, M. Carrascal, J. Abian, J. Vives, J. Yélamos, F. Lozano. Biochemical Characterization Of Recombinant And Circulating Human Spa. Tissue Antigens 63, 335-344 (2004)   
20 T.Lamparter, M.Carrascal, N.Michael, E.Martinez, G.Rottwinkler and J.Abian. The Biliverdin Chromophore Binds Covalently to A Conserved Cysteine Residue in the N-terminus of Agrobacterium Phytochrome Agp1. Biochemistry 43, 3659-3669 (2004)   
21 A. Muntasell, M. Carrascal, L. Serradell, P. vanVeelen, F.Verrek, F. Koning, J. Abian and D. Jaraquemada. Disecction of the HLA-DR4 Peptide Repertoire in Endocrine Epithelial Cells: strong Influence of Ii and HLA-DM Expression On the Nature of Ligands. J.Immunol 173, 1085-93 (2004).   
22 A. Pitarch, J. Abian, M. Carrascal, M. Sánchez, C. Nombela and C.Gil. Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies. Proteomics  4, 3084-3106, (2004)   
23 J. López-Hellín, R. Gonzalo, M.Tejeda, M. Carrascal, M.R. Vilà, J. Abián and E. García-ArumíTranscriptomic and proteomic analysis of liver and muscle alterations caused by surgical stress. Clinical science 108, 167-178 (2005).   
24 B.Esteban, M.Carrascal, J.Abian and T.Lamparter. Light induced conformational changes of cyanobacterial phytocrome Cph1 probed by limited proteolysis and Autophosphorylation. Biochemistry 44, 450-461 (2005).   
25 A.Romero-Ruiz, M.Carrascal, J.Alhama, J.L.Gómez-Ariza, J.Abian and J. López-Barea. Utility of Proteomics to assess pollutant response of clams from the Doñana bank of Guadalquivir Estuary (SW Spain). Proteomics 6, S245-S255 (2006)   
26 E.Pavón,  P.Muñoz, A.Lario, V.Longobardo, M.Carrascal, J.Abián, A.Martin, J.L.Callejas-Rubio, R.Sola, E.Raya-Alvarez, N.Ortego-Centeno, M.Zubiaur and J.Sancho. Proteomic analysis of plasma from patients with Systemic Lupus Erythematosus: Increased presence of haptoglobin a2 polypeptide chains over the a1 isoforms. Proteomics 6, S282-S292 (2006)   
27 I.Vendrell, M.Carrascal, M.-T.Vilaró, J.Abián and C.Suñol. Cell viability and proteomic analysis in cultured neurons exposed to methylmercury. Human and experimental Toxicology 26, 263-272 (2007)   
28 R.Daniel, L.Chevolot, M.Carrascal, B.Tissota, P.A.S. Mourão, J.Abian. Electrospray ionization mass spectrometry of oligosaccharides derived from fucoidan of Ascophyllum nodosum. Carbohydrate Research 342, 826-834 (2007)   
29 Alvarez I, Carrascal M, Canals, F., Muixi, L., Abian, J. and Jaraquemada D. Análisis of the HLA class I associated peptide repertoire in a hepatocellular carcinoma cell line reveals tumor-specific peptides as putative targets for immunotherapy. Proteomics Clin. Appl. 1, 286-298 (2007)   
30 Montes-Nieto, R., Fuentes-Almagro, C.A., Bonilla-Valverde, D., Prieto-Alamo, M.J., Jurado, J., Carrascal, M., Gómez-Ariza J.L., López-Barea J. and Pueyo C. Proteomics in free-living Mus spretus to monitor terrestrial ecosystems. Proteomics 7(23):4376-87 (2007)    
31 Pereira, A., Ruiz, J., Carrascal, M., Abian, J. and Sanz-Medel, A. Absolute and site-specific quantification of protein phosphorylation using a simple phosphorus standard and Elemental Mass Spectrometry. Anal.Chem. 80 (5), 1777-1787 (2008)  
32 L.Muixí, M.Carrascal, I.Alvarez, X.Daura, M.P.Armengol, C.Pinilla, J.Abian, R.Pujol-Borrell, D.Jaraquemada. Ex-vivo analysis of HLA Class II Natural Ligands in autoimmune Thyroid J. Immunol. 181, 795-807 (2008)  
33 Carbó C, Arderiu G, Escolar G, Fusté B, Cases A, Carrascal M, Abián J, Diaz-Ricart M. Differential expression of proteins from cultured endothelial cells esposed to uremic versus normal serum. Am J Kidney Dis. 51:603-612 (2008)  
34 Casanovas A, Carrascal M, Abian J, Lopez-Tejero D, Llobera M. Application of proteomics tools to detect the non-specificity of a polyclonal antibody against lipoprotein lipase. J. Proteome Res. 7(9), 4173-7 (2008)   
35 Acín P, Carrascal M, Abian J, Guerrero A, Quero C. Differential antennal proteins in males and females of the Mediterranean corn borer, Sesamia nonagrioides, an importan crop pest. Insect Biochem. Mol. Biol, 14, 1-9 (2008)   
36 Carrascal M, Ovelleiro D, Casas V, Gay M, Abian J. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. J. Proteome Res. 7, 5167-5176 (2008)   
37 Casanovas A, Carrascal M, Abian J, Lopez-Tejero D, Llobera M. Lipoprotein lipase presents multiple charge isoforms. J. Proteomics 13, 1031-1039 (2009)   
38 Ovelleiro D, Carrascal M, Casas V, Abian J. LymPHOS: Desing of a phosphosite database of primary human T cells. Proteomics 9, 3741-3751 (2009)   
39 Díez-Vives C, Gay M, García-Matas S, Comellas F, Carrascal M, Abian J, Cristòfol R, Sanfeliu C. Proteomis study of neuron and astrocyte cultures from senescence accelerated mouse SAMP8. J. Neurochem. 11, 945-955 (2009)   
40 Casanovas A, Carrascal M, Abián J, Lopez-Tejero MD, Llobera M. Lipoprotein lipase is nitrated in vivo after lipopolysaccharide challenge. Free Radical Biology and Medicine 47, 1553-1560 (2009) m
41 Vendrell I, Carrascal M, Campos F, Abian J, Suñol C. Methylmercury disrupts the balance between phosphorylated and non-phosphorylated cofilin in primary cultures of mice cerebellar granule cells. A proteomic study. Toxicology and Applied Pharmacology 242, 109-118 (2010)  
42 Gay M, Carrascal M, Gorga M, Parés A, Abian J. Characterization of peptides and proteins of therapeutic human serum albumin. Proteomics 10, 1-10 (2010)  
43 Ponce J, Brea D, Carrascal M, Guirao V, Degregorio-Rocasolano N, Sobrino T, Castillo J, Dávalos A, Gasull T. The effect of simvastatin on the proteome of detergent resistant membrane domains: decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate. Proteomics 10, 1954-1965 (2010).  
44 Bañom-Maneus E, Diekmann F, Carrascal M, Quintana LF, Moya-Rull D, Bescós M, Ramírez-Bajo MJ, Rovira J, Gutierrez-Dalmau A, Solé-Gonzalez A, Abian J, Campistol JM. Two-dimensional difference gel electrophoresis urinary proteomics profile in the search of nonimmune chronic allograft dysfunction biomarkers. Transplantation 89(5), 548-558 (2010)  
45 Gay M, Parés A, Carrascal M, Bosch-i-Crespo P, Gorga M, Mas A, Abian J. Proteomic analysis of polypeptides captured from blood during extracorporeal albumin dialysis in patiens with resistant pruritus. PLoS ONE 6(7), e21850 (2011)  
46 Martiañez T, Carrascal M, Lamarca A, Segura M, Durany D, Masgrau R, Ab ian J, Gella A. UTP affects schwannoma cell line proteome through P2Y receptors leading to cytoskeletal reorganization. Proteomics 12, 145-156 (2012)  
47 Pavón EJ, García-Rodríguez S, Zumaquero E, Perandrés-López R, Rosal-Vela A, Lario A, Longobardo V, Carrascal M, Abian J, Callejas-Rubio JL, Ortego-Centeno N, Zubiaur M, Sancho J. Increases expression of phosphorylated S100A9 isoforms in mononuclear cells from patiens with systemic lupus erythematosus; A proteomic signature for circulating lowdensity granulocytes. J. Proteomics 75, 1778-1791 (2012)  
48 Amézqueta S, Galán E, Fuguet E, Carrascal M, Abian J, Torres JL. Determination of D.fagomine in buckwheat and mulberry by cation exchange HPLC/ESI-Q-MS. Anal. Bioanal. Chem. 402 (%), 1953-1960 (2012)  
49 Izquierdo-Alvarez A, Ramos E, Villanueva J, Hernansanz-Agustin P, Fernándes-Rodriguez R, Tello D, Carrascal M, Martinez-Ruiz A. Differential redox proteomics allows identification of proteins reversibly oxidized at cysteine residues in endothelial cells in response to acute hypoxia. J. Proteomics 75(17), 5449-5462 (2012)  
50 Pavón E, Zumaquero E, Rosal-Vela A, Khoo KM, Cerezo-Wallis D, García-Rodríguez S, Carrascal M, Abian J, Graedd R, Callejas-Rubio JL, Ortego-Centeno N, Malavasi F, Zubiaur M, Sancho J. Increased CD 38 expression in T cells and circulating anti-CD38 IgG autoantibodies differentially correlate with distinct cytokine profiles and disease activity in systemic lupus arythematosus patiens. Cytokine 62(2), 232-243 (2013)  
51 Amézqueta D, Galán E, Vila-Fernández I, Pumarola S, Carrascal M, Abián J, Ribas-Barba L, Serra-Majem L, Torres JL. The presence of D-fagomine in the human diet from buckwheat-based foodstuffs. Food Chem 136(3-4), 1316-1321 (2013)  
52 Martínez-Bartolomé S, Deutsch EW, Binz PA, Jones AR, Eisenacher M, Mayer G, Campos A, Canals F, Bech-Serra JJ, Carrascal M, Gay M, Paradela A, et al. Guidelines for reporting quantitative mass spectrometry based experiments in proteomics. J, Proteomics 95, 84-88 (2013)  
53 Collado JA, Alvarez I, Ciudad MT, Espinosa G, Canals F, Pujol-Borrell R, Carrascal M, Abian J, Jaraquemada D. Composition of the HLA-DR-associated human thymus peptidome. Eur. J. Immunol. 43, 2273-2282 (2013)  
54 Villanueva J, Carrascal M, Abian J, Protein quantification using isotope dilution mass spectrometry. J. Proteomics 96, 184-199 (2014)  
55 Vialas V, Sun Z, Loureiro Y, Penha CV, Carrascal M, Abian J, Monteoliva L, Deutsch EW, Aebersold R, Moritz R, Gil C. A Candida albicans PeptideAtlas. J. Proteomics 97, 62-68 (2014)  
56 Segura V, Medina-Aunon A, Mora I, Martínez-Bartolome S, Abian J, Aloria K, Antúnez O, Arizmendi JM, Azkargorta M, Barcelo-Batllori S, Beaskoetsea J, Bech-Serra JJ, Banco F, Monteiro MB, Cáceres D, Canals F, Carrascal M at al. Surfing transcriptomic landscapes. A step beyond the annotation of Chromosome 16 proteome. J. Proteome Res. 13, 158-172 (2014)  
57 EspinosaG, Collado JA, Scholz E, Mestre-Ferrer A, Kuse N, Takiguchi M, Carrascal M, Canals F, Pujol-Borrell R, Jaraquemada D, Alvarez I. Peptides presented by HLA class I molecules in the human thymus. J, Proteomics 94, 23-36 (2013)  
58 Badia-Villanueva M, Carulla P, Carrascal M, Abian J, Llobera M, Casanovas A, Lopez-Tejero D. Lipoprotein lipase isoelectric point isoforms in humans. Biochem, Biophys. Res. Commun. 445(2), 480-485 (2014)  
59 Navarro P, Trevisan-Herraz M, Bonzon-Kulichenko E, Nuñez E, Martinez-Acedo P, Pérez-Hernández D, Jorge I, Mesa R, Calvo E, Carrascal M, Hernáez ML, García F, Bárcena JA, Ashman K, Abian J, Gil C, Redondo JN, Vázquez J. General statistical framework for quantitative proteomics by stable isotope labeling. J Proteome Res. 13(3), 1234-1247 (2014)  
60 Rocha B, Calamia V, Casas V, Carrascal M, Blanco FJ, Ruiz-Romero C. Secretome analysis of human mesenchymal stem cells undergoing chondrogenic differentiation. J. Proteome. Res 13(2), 1045-1054 (2014)  
61 Gallardo O, Ovelleiro D, Gay M, Carrascal M, Abian J. A collection of open source applications for mass spectrometry data mining. Proteomics 14(20), 2275-2279 (2014)  
62 Alvarez I, Collado JA, Colobran R, Carrascal M, Ciudad MT, Canals F, James EA, Kwok WW, Gärtner M, Kyewski B, Pujol-Borrell R, Jaraquemada D. Central T tolerance: identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome. J. Autoimmun. 2015 Apr 21 doi: 10.1016/j.jaut 2015 03 004.  
63 T.D. Nguyen, O. Vidal-Cortes, O. Gallardo, J. Abian and M. Carrascal. LymPHOS 2.0: an update of a phosphosite database of primary human T cells. Database (2015) Vol. 2015 doi: 10.1093/database/bav115
64 T.D. Nguyen, M. Carrascal, O. Gallardo, O. Vidal-Cortes, V. Casas, M. Gay, V.Ch. Phan, J. Abian. The phosphoproteome of Human Jurkat T cell clones upon costimulation with anti-CD3/anti-CD28 antibodies.J. Proteomics 2016, 10, 190-198. doi: 10.1016/j.jprot.2015.10.029  
65 Vialas V, Sun Z, Reales-Calderón JA, Hernáez ML, Casas V, Carrascal M, Abián J, Monteoliva L, Deutsch EW, Moritz RL, Gil C. A comprehensive Candida albicans Peptide Atlas build enables deep proteome coverage. J. Proteomics 2016, 10, 122-30. doi: 10.1016/j.jprot.2015.10.019  
66 Scholz E, Mestre-Ferrer A, Daura X, García-Medel N, Carrascal M, James EA, Kwok WW, Canals F, Alvarez I. A comparative analysis of the peptide repertoires of HLA-DR molecules differentially associated to rheumatoid arthritis. Arthritis Rheumatol. 2016 May 9. doi: 10.1002/art.39736.  

M.Carrascal and J.Abian. Capillary Separations HPLC of Peptides and Proteins: Methods and Protocols Aguilar M.-I (editor) Methods in Molecular Biology vol 251, Chapter 10, pp 143-164 , Humana Press Inc. NJ, USA (2004)    
J.Abian and M. Carrascal. Quantitative Peptide Determination Using Column-Switching Capillary Chromatography Interfaced with Mass Spectrometry. Emerging Technologies in Protein and Genomic Material Analysis. G. Marko-Varga and P. Oroszlan (Eds) J.Chromatography Library vol 68. Chapter 4, pp 39-73 (Elsevier Science BV 2003)  
3 R.E. Calaf, J. Peña, M.Carrascal, S.Paituby, N.Reig, R. Prieto, Y.Castaño, BC Blount, M Posada de la Paz, E.Gelpi, J.Abian. Chemical analyses of TOS oils. The Toxic Oil Syndrome. Ten years of progress. B. Terracini (editor). Annex 4 part 1, pp 145-160. WHO Regional Office for Europe. Copenhagen (2004) ISBN 92 890 1063 0  
4 J Abian, M Gay, M Carrascal. Estrategias en proteómica de alto rendimiento (high throughput). Caracterizacion de proteomas, LC-MS/MS. FDR. Manual de Proteómica. Sociedad Española de Proteómica. 2014.  
5 M Gay, M Carrascal, J Abian. Analizadores de masa en proteómica. Principios operacionales y parámetros de rendimiento. I. Triple cuadrupolo, QTrap. Manual de Proteómica. Sociedad Española de Proteómica. 2014.  
6 M Carrascal, J Abian, M Gay. Fosfoproteómica. Técnicas de enriquecimiento de fosfopéptidos. Métodos espectrométricos para la identificación de fosfopéptidos. Manual de Proteómica. Sociedad Española de Proteómica. 2014.